Women's heart health

Health Equity

Health Equity

Heart health is often overlooked – by women themselves, medical professionals, and employer organizations – as a major women’s health concern, which can be deadly. In fact, heart disease is the top cause of death for women in the U.S. It’s also frequently perceived as more of a concern for men, but data proves otherwise.

Resources About Health Equity

WHITEPAPER

Addressing Inequities in Women’s Heart Health

Learn how digital health can help improve heath equity in your organization.
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Report

Reducing Heart Health Inequities

Learn how digital therapeutics are breaking down barriers to care.
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report

Can a Digital Program Contribute to Health Equity

A summary of a study of 15,361 Hello Heart users across sex, language, age, race & ethnicity. Published in American Heart Association's Hypertension Journal.
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Women deserve women-centered care 

Many current heart health approaches are adapted from practices based on male physiology. Women are not “small men.” While their hearts are smaller and their blood vessels narrower than men’s,1 other important differences impact women’s heart health and management.

  • Plaque/cholesterol is deposited differently for women and men. Women are more likely to have cholesterol buildup in the smallest blood vessels.2
  • Significant heart disease in women develops about seven to 10 years later than in men, and increases two- to threefold after the age of 50.3
  • Women’s cholesterol scales are different because women have higher levels of HDL cholesterol than men. The female sex hormone estrogen seems to boost this good cholesterol.4 
  • Some heart attack symptoms are the same regardless of sex, but several are unique to women.5

Acknowledging and addressing these crucial differences is a major step forward to better health and equity.

Learn more about high blood pressure and high cholesterol in women.

Learn more about women’s heart attack symptoms.

Black women are at particular risk

The health of non-White people and especially non-White women has been damaged by systemic, long-term inequities in care access, affordability, and appropriateness. Ongoing institutional racism and differential participation in research have produced additional enduring harm.

These disparities disproportionately impact Black women.

Confronting this reality is imperative in the quest for equitable and inclusive workplaces because  Black women have the highest labor participation rate among women. 7 

  • Black women are nearly 50% more likely to have high blood pressure compared to non-Hispanic White women and are less likely to have it under control.8
  • Black Americans are 30% more likely to die from heart disease than non-Hispanic White adults.9
  • The persistent underrepresentation of non-White women in major cardiovascular research and clinical trials contributes to under-treatment and ineffective care.10

Multiple factors make women more likely to die from a “cardiac event”

Women are up to twice as likely to die from complications of a heart attack than men.11 They’re also more likely to have a second heart attack or a stroke.12 

One reason: a woman’s first cardiac “event” usually happens later in life when other conditions and comorbidities like diabetes or Chronic Obstructive Pulmonary Disease (COPD) are more likely to co-exist.13 

Another factor: time to treatment. Women wait to seek care 37 minutes longer than men.14 In a situation where seconds count, delaying care is dangerous. 

Women may be slow to get help because they don’t know their symptoms are heart-related. One study found that over half of women having a heart attack assumed that their symptoms are not heart-related, with 21% of those women instead attributing their symptoms to stress or anxiety. The same study also found that providers also often misdiagnose heart attacks in women, with 53% of women reporting that their provider did not think their heart attack symptoms were heart-related.15 

Women face more barriers to heart health

Even when they do seek care, women encounter additional barriers to health, including:

  • Medical gaslighting and physician lack of knowledge: A recent NY Times article highlighted the prevalence of healthcare providers ignoring or dismissing symptoms of women, including the story of one woman who had to see multiple providers before being properly diagnosed and getting potentially life-saving heart surgery.16 In one study focused on heart attack, 53% of women reported that their provider did not think their heart attack symptoms were heart-related.17
  • Unconscious systemic and personal bias: Research shows that providers’ implicit gender bias contributes to disparities in administering cardiac tests for people being evaluated for Coronary Artery Disease (CAD),18 
  • Research gap: Clinical research practice and the research agenda were set by White men for centuries. Until 2001, most studies enrolled White men and used male lab rats for animal research. This means that the majority of medical research up to that point excluded the majority of people (women make up 50.5% of the American population) and anyone who is non-White.19

Many heart disease risk factors are modifiable

70% of heart disease cases and deaths are caused by modifiable risk factors20 

A woman’s heart health is influenced by several factors that can change with behavior modification and medication. Pinpointing hypertension is particularly vital since 44% of adult women have high blood pressure,21 and Black women have about 40% higher rates than white women.22

Personalized interventions and ongoing support can help women understand and address the top and most prevalent risk factors for heart disease: high blood pressure and high cholesterol.23

Footnotes
  1. Huxley VH. Sex and the cardiovascular system: the intriguing tale of how women and men regulate cardiovascular function differently. Adv Physiol Educ. 2007 Mar; 31(1): 17–22. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298433/#. Accessed March 29, 2023.
  2. (1) Tian J, Wang X, Tian J, Yu B. Gender differences in plaque characteristics of nonculprit lesions in patients with coronary artery disease. BMC Cardiovasc Disord. 2019 Feb 26;19(1):45. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390304. Accessed December 28, 2022. (2) Fairweather D. Sex differences in inflammation during atherosclerosis. Clin Med Insights Cardiol. 2015 Apr 19;8(Suppl 3):49-59. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405090.Accessed December 28, 2022. (3) Angina in Women Can Be Different Than Men. American Heart Association Web site. https://www.heart.org/en/health-topics/heart-attack/angina-chest-pain/angina-in-women-can-be-different-than-men. Accessed December 28, 2022.
  3. (1) Rodgers JL, Jones J, Bolleddu SI, Vanthenapalli S, Rodgers LE, Shah K, Karia K, Panguluri SK. Cardiovascular Risks Associated with Gender and Aging. J Cardiovasc Dev Dis. 2019 Apr 27;6(2):19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616540. Accessed December 28, 2022. (2) Garcia M, Mulvagh SL, Merz CN, Buring JE, Manson JE. Cardiovascular Disease in Women: Clinical Perspectives. Circ Res. 2016 Apr 15;118(8):1273-93. https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.116.307547. Accessed December 28, 2022.
  4. (1) Why Cholesterol Matters for Women, Johns Hopkins Medicine Web site. https://www.hopkinsmedicine.org/health/wellness-and-prevention/why-cholesterol-matters-for-women. Accessed December 13, 2022. (2) Guetta V, Cannon RO 3rd. Cardiovascular effects of estrogen and lipid-lowering therapies in postmenopausal women. Circulation. 1996 May 15;93(10):1928-37. https://www.ahajournals.org/doi/full/10.1161/01.cir.93.10.1928#. Accessed December 28, 2022. (3) Swiger KJ, Martin SS, Blaha MJ, Toth PP, Nasir K, Michos ED, Gerstenblith G, Blumenthal RS, Jones SR. Narrowing sex differences in lipoprotein cholesterol subclasses following mid-life: the very large database of lipids (VLDL-10B). J Am Heart Assoc. 2014 Apr 22;3(2):e000851. https://www.ahajournals.org/doi/pdf/10.1161/JAHA.114.000851. Accessed December 28, 2022.
  5. (1) Heart Attack: Men vs. Women. The Heart Foundation Web site. https://theheartfoundation.org/2017/03/29/heart-attack-men-vs-women/. Published March 29, 2017. Accessed December 13, 2022. (2) Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D’Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction: Evidence from the VIRGO Study (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients). Circulation. 2018;137:781–790. https://doi.org/10.1161/CIRCULATIONAHA.117.031650. Accessed December 28, 2022.
  6. What is Health Equity? CDC Web Site. https://www.cdc.gov/healthequity/whatis/index.html. Accessed March 29, 2023.
  7. U.S. Department of Labor. 5 Facts About Black Women in the Labor Force.
  8. (1) U.S. Department of Health & Human Services - Office of Minority Health Web site. Heart Disease and African Americans. https://minorityhealth.hhs.gov/omh/browse.aspx?lvl=4&lvlid=19. Accessed December 13, 2022. (2) Thomas SJ, Booth JN 3rd, Dai C, Li X, Allen N, Calhoun D, Carson AP, Gidding S, Lewis CE, Shikany JM, Shimbo D, Sidney S, Muntner P. Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study. J Am Heart Assoc. 2018 Jul 11;7(14):e0
  9. (1) U.S. Department of Health & Human Services - Office of Minority Health Web site. Heart Disease and African Americans. https://minorityhealth.hhs.gov/omh/browse.aspx?lvl=4&lvlid=19. Accessed December 13, 2022. (2) Graham G. Disparities in cardiovascular disease risk in the United States. Curr Cardiol Rev. 2015;11(3):238-45. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558355. Accessed December 13, 2022.
  10. Kardie Tobb, Madison Kocher, Renée P. Bullock-Palmer. Underrepresentation of women in cardiovascular trials- it is time to shatter this glass ceiling, American Heart Journal Plus: Cardiology Research and Practice, Volume 13, 2022, 100109, ISSN 2666-6022. https://doi.org/10.1016/j.ahjo.2022.100109. Accessed December 13, 2022.
  11. Shah T, Haimi I, Yang Y, Gaston S, Taoutel R, Mehta S, Lee HJ, Zambahari R, Baumbach A, Henry TD, Grines CL, Lansk A, Tirziu D. Meta-Analysis of Gender Disparities in In-hospital Care and Outcomes in Patients with ST-Segment Elevation Myocardial Infarction. Am J Cardiol. 2021;147:23-32. https://doi.org/10.1016/j.amjcard.2021.02.015. Accessed December 13, 2022.
  12. Woodward M. Cardiovascular Disease and the Female Disadvantage. Int J Environ Res Public Health. 2019 Apr 1;16(7):1165. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479531. Accessed December 13, 2022.
  13. (1) Shufelt CL, Pacheco C, Tweet MS, Miller VM. Sex-Specific Physiology and Cardiovascular Disease. Adv Exp Med Biol. 2018;1065:433-454. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768431. Accessed December 13, 2022. (2) Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Shay CM, Spartano NL, Stokes A, Tirschwell DL, VanWagner LB, Tsao CW; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. Circulation. 2020 Mar 3;141(9):e139-e596. https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000757. Accessed December 13, 2022.
  14. Gender differences in patient and system delay for primary percutaneous coronary intervention: current trends in a Swiss ST-segment elevation myocardial infarction population. Eur Heart J Acute Cardiovasc Care. 2019;8(3):283-290.  https://doi.org/10.1177/2048872618810410. Accessed December 13, 2022.
  15. Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D’Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction: Evidence from the VIRGO Study (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients). Circulation. 2018;137:781–790. https://doi.org/10.1161/CIRCULATIONAHA.117.031650. December 13, 2022
  16. Moyer, Melinda W. “Women Are Calling Out Medical Gaslighting”. NY Times, March 28, 2022. https://www.nytimes.com/2022/03/28/well/live/gaslighting-doctors-patients-health.html
  17. Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D’Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction: Evidence from the VIRGO Study (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients). Circulation. 2018;137:781–790. https://doi.org/10.1161/CIRCULATIONAHA.117.031650. December 13, 2022
  18. (1) Implicit Gender Bias and the Use of Cardiovascular Tests Among Cardiologists. https://www.ahajournals.org/doi/10.1161/JAHA.117.006872. Accessed December 13, 2022. (2) Daugherty SL, Blair IV, Havranek EP, Furniss A, Dickinson LM, Karimkhani E, Main DS, Masoudi FA. Implicit Gender Bias and the Use of Cardiovascular Tests Among Cardiologists. J Am Heart Assoc. 2017 Nov 29;6(12):e006872. https://pubmed.ncbi.nlm.nih.gov/29187391. Accessed December 13, 2022.
  19. (1) Merone L, Tsey K, Russell D, Nagle C. Sex Inequalities in Medical Research: A Systematic Scoping Review of the Literature. Womens Health Rep (New Rochelle). 2022 Jan 31;3(1):49-59. doi: 10.1089/whr.2021.0083. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812498. Accessed December 13, 2022. (2) Holdcroft A. Gender bias in research: how does it affect evidence based medicine? J R Soc Med. 2007 Jan;100(1):2-3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761670. Accessed December 13, 2022.
  20. Yusuf S, Joseph P, Rangarajan S, Islam S, Mente A, Hystad P, Brauer M, Kutty VR, Gupta R, Wielgosz A, AlHabib KF, Dans A, Lopez-Jaramillo P, Avezum A, Lanas F, Oguz A, Kruger IM, Diaz R, Yusoff K, Mony P, Chifamba J, Yeates K, Kelishadi R, Yusufali A, Khatib R, Rahman O, Zatonska K, Iqbal R, Wei L, Bo H, Rosengren A, Kaur M, Mohan V, Lear SA, Teo KK, Leong D, O'Donnell M, McKee M, Dagenais G. Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study. Lancet. 2020 Mar 7;395(10226):795-808. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32008-2/fulltext. Published March 7, 2020. Accessed December 13, 2022.
  21. Facts About Hypertension. CDC Web site. https://www.cdc.gov/bloodpressure/facts.htm. Published July 12, 2022. Accessed December 13, 2022.
  22. Heart Disease and African Americans. Office of Minority Health Web site. https://minorityhealth.hhs.gov/omh/browse.aspx?lvl=4&lvlid=19#:~:text=Although%20African%20American%20adults%20are,to%20non%2DHispanic%20white%20women. Accessed December 13, 2022.
  23. (1) Davis J. High Cholesterol and High Blood Pressure. WebMD Web site. https://www.webmd.com/cholesterol-management/high-cholesterol-and-high-blood-pressure. Published June 7, 2021. Accessed December 13, 2022. (2) The top health conditions that increase risk for heart disease are high blood pressure, high LDL cholesterol, diabetes, and obesity. (Source: Know Your Risk for Heart Disease. CDC Web site.