Peer-Reviewed Research in the American Journal of Preventive Cardiology Among the Largest-Ever Studies of a Digital Health Intervention for Women’s Health
Menlo Park, Calif. – Monday, August 4, 2025 — A new peer-reviewed study in the American Journal of Preventive Cardiology shows Hello Heart’s digital heart health program is associated with significant blood pressure reductions among women with hypertension, including those in perimenopause and postmenopause — life stages where cardiovascular risk sharply increases but is often under-addressed in routine care.
The study, titled, “Blood Pressure Reduction by Gender and Menopause Status Among Hypertensive Participants of a Mobile Health Cardiovascular Risk Self-Management Program,” analyzed data from more than 48,000 participants (55% women) enrolled in the Hello Heart program between July 2015 and September 2023. This makes it one of the largest studies of a digital health intervention’s impact on women’s health to-date.
Key Findings
- While the program proved effective for both women and men, women using Hello Heart experienced even greater blood pressure reductions, even after adjusting for age, medication use, and other factors.
- Women in menopause, despite starting with higher baseline blood pressure, achieved improvements on par with their premenopausal peers.
- Participants with very high blood pressure (≥140 mmHg) saw sustained reductions over 12 months, with women in this high-risk group lowering their numbers more than matched male participants.
“This study is a crucial step forward in understanding how to support women at a time when they face heightened cardiovascular risk,” said lead author Jayne Morgan, MD, a cardiologist and VP of Medical Affairs at Hello Heart. “We’ve known for years that menopause is a turning point for heart health, but until now, there’s been little data on scalable, effective ways to intervene during this phase. These findings show that digital tools can help close the gap.”
The Hello Heart program includes a connected blood pressure monitor, medication adherence tools, and AI-driven, personalized coaching, including educational heart health content tailored specifically for menopausal women. The study highlights how these targeted features may empower women to better manage their cardiovascular health and sustain behavior change over time.
“Menopause is a time of change, but it shouldn’t be the beginning of cardiovascular decline,” said co-author Erin Michos, MD, MHS, Professor of Medicine and Director of Women’s Cardiovascular Health at Johns Hopkins University School of Medicine. “Accessible digital health programs like Hello Heart’s can empower women with actionable tools to reduce risk of a serious event.”
“We need to think of menopause as a window of opportunity when it comes to heart health and get proactive about helping women understand their risk and take action,” added co-author Martha Gulati, MD, MS, Director of Cardiovascular Prevention, and Associate Director of the Barbra Streisand Women’s Heart Center at Cedars-Sinai. “This is a strong example of how we can do that.”
About Hello Heart
Hello Heart is on a mission to change the way people care for their hearts. The company provides the first connected heart monitor, pill box, and app to help people track and manage their heart health. With Hello Heart, people are empowered to take steps to control their risk of heart disease, the leading cause of death in the United States. Peer-reviewed studies show that high-risk users of Hello Heart have seen meaningful drops in blood pressure, cholesterol and even weight.
Recognized as the digital leader in preventive heart health, Hello Heart is trusted by more than 150 leading Fortune 500 and government employers, national health plans, and labor organizations such as 3M, Lenovo, Northwestern Mutual, and the City of Fort Worth. Hello Heart clients can save $1,709 per enrolled user annually according to a peer-reviewed study published in leading health economics journal Value In Health.
Founded in 2013, Hello Heart has raised more than $138 million from top venture firms including Khosla Ventures, IVP, and Stripes. Hello Heart is a best-in-class solution on the American Heart Association’s Innovators’ Network, CVS Health Point Solutions Management offering, and many other leading health solution platforms. Visit www.helloheart.com for more information.
